Critical Process Filtration Blog

Critical Insights

Blog Feature

Filter System Design | How-To | Problem Solving

DEVELOPMENT, SCALE-UP, AND VALIDATION OF PHARMACEUTICAL FILTRATION PROCESSES Our Technical Service Team performs application testing for a wide variety of fluids from water to complex chemical solutions. No matter what industry the customer is part of, we carefully document our test results and make recommendations based on those results. We get it right the first time.  For pharmaceutical applications, whether removing particles from ingredients entering the plant or sterilizing parenteral products, the testing and documentation we routinely create help show the consistent performance required for validation of the process.

Blog Feature

How-To | Integrity Testing | Pressure Decay Test

By: Critical Process Filtration
May 12th, 2022

A simpler integrity test for less critical applications is a Pressure Decay Test. This requires the same air (or nitrogen) source and an accurate pressure gauge but does not require a mass flow meter. This type of test can be performed before and after use and is sensitive enough to detect very small leaks.

Blog Feature

Final Filtration | Bacteria Reduction/Removal | Beer Filtration | Beverage Processing | How-To | Problem Solving

By: Critical Process Filtration
May 16th, 2019

The alcohol, low oxygen content, relatively low pH, hops extracts (alpha-acids) and dissolved carbon dioxide in beer inhibit the growth of pathogenic bacteria. That is why beer has been a safe drinking alternative for so many centuries. However, there are microorganisms that can survive and even thrive in beer and spoil the flavor and aroma of any good brew.

Blog Feature

How-To | Reduce Operating Costs | Improve Filter Performance

By: Critical Process Filtration
May 16th, 2019

We hear this question on a regular basis, and although some may quip “buy cheaper filters”  we contend that installing the RIGHT filter is the key to doing both simultaneously.  Our experience with customers in different industries and applications has shown that those who spent the time to  assess their process and test alternative filters are the ones that succeeded in finding cost savings and process performance improvement. Since every application has its nuances and every company has their standards, in this article, we will offer a more generic and holistic view of the question;